Download e-book for kindle: Cell Polarity and Subcellular RNA Localization (Results and by Dietmar Richter

By Dietmar Richter

Selective cytoplasmic organelle and protein concentrating on has lengthy been inspiration to represent the only determinant of mobile polarity and complexity. This view has been replaced, although, by way of the invention of differential subcellular RNA distribution styles. during the last decade it has develop into transparent that selective mRNA sorting and translation contributes to an accumulation of cognate proteins at discrete mobile websites. during this booklet, numerous structures are mentioned (e.g. Xenopus oocytes, mammalian mind, invertebrate apprehensive process) when it comes to RNA trafficking, RNA-targeting sequences (cis-elements) and RNA-transporting proteins (trans-factors), activity-dependent translational rules and the importance of the cytoskeleton for neuronal functionality and plasticity. It additionally discusses nucleocytoplasmic export of mRNA and viral RNA as one other instance of subcellular RNA kinesis.

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